研究業績

バイオ情報工学研究チーム

論文

2025 （2018年以降）

*Corresponding Author

  1. San, M.H., Kawamura, Y., Kimura, K., Witharana, E.P., Shimogiri, T., Fujiyoshi, E. and Nagano, Y.:  Gene tree conflict in chloroplast-based phylogenies in Pyropia species. Phycological Res., 73, 79-91 doi.org/10.1111/pre.12576 (2025)
  2. Witharana, E.P., Iwasaki, T., San, M.H. et al.: Subfamily evolution analysis using nuclear and chloroplast data from the same reads. Sci Rep., 15, 687 doi.org/10.1038/s41598-024-83292-9 (2025)
  3. Hirano, Y., Kojima, N. Sakurai, H., Saito, E., Nankai, H., and Komatsu, Y.: Analysis of the Effects of Sugar Modifications on RNA Chemical Ligation Reactions. ChemBioChem., 26, 2500263. DOI:10.1002/cbic.202500263. (2025).
  4. Mie, Y., Mikami, C., Yasutake, Y., Shigemura, Y., Yamashita, and T., Tsujino, H.: Electrochemical Analysis and Inhibition Assay of Immune-Modulating Enzyme, Indoleamine 2,3-Dioxygenase. Pharmaceuticals (Basel)., 18, 352. DOI:10.3390/ph18030352. (2025).
  5. Akiyama, K., Okabe, H., Motomura, T., Matsuda N. and Mie, Y.: Efficacy of AuNP film electrode fabricated with surfactant-free solution for direct electron transfer control of redox protein. Electrochem. Commun., 161, 107695. DOI:10.1016/j.elecom.2024.107695 (2025).
  6. San, M.H., Kawamura, Y., Kimura, K. et al.: Characterization and organelle genome sequencing of Pyropia species from Myanmar. Sci Rep., 13, 15677 doi.org/10.1038/s41598-023-42262-3 (2023)
  7. Mie, Y., Okabe, H., Mikami, C., Motomura, T. and Matsuda, N.: Nanostructured gold thin film electrode derived from surfactant-free gold nanoparticles for enhancement in electrocatalysis. Electrochem. Commun., 16, 107415. DOI:10.1016/j.elecom.2022.107415. (2023).
  8. Taniguchi T, Okuno M, Shinoda T, Kobayashi F, Takahashi K, Yuasa H, Nakamura Y, Tanaka H, Kajitani R, Itoh T. (2023) GINGER: An integrated method for high-accuracy prediction of gene structure in higher eukaryotes at the gene and exon level. DNA Res dsad017. doi: 10.1093/dnares/dsad017
  9. Hirano, Y., and Komatsu, Y.: Promotion of cytoplasmic localization of oligonucleotides by connecting cross-linked duplexes. RSC Adv., 12, 24471. DOI:10.1039/D2RA04375K. (2022).
  10. Abdelhady, A. M., Hirano, Y., Onizuka, K., Okamura, H., Komatsu, Y., and Nagatsugi, F.: Synthesis of Crosslinked 2′-OMe RNA Duplexes Using 2-Amino-6-Vinylpurine and Their Application for Effective Inhibition of miRNA Function. Current Protocols. 2 e386. DOI:10.1002/cpz1.386. (2022)
  11. Mie Y., Katagai, S. and Mikami, C.: Electrochemical Molecular Conversion of α-Keto Acid to Amino Acid at a Low Overpotential Using a Nanoporous Gold Catalyst. Int. J. Mol. Sci., 22, 9442. DOI:10.3390/ijms22179442. (2021).
  12. Abdelhady, A. M., Hirano, Y., Onizuka, K., Okamura, H., Komatsu, Y., and Nagatsugi, F.: Synthesis of crosslinked 2′-OMe RNA duplexes and their application for effective inhibition of miRNA function. Bioorganic and Medicinal Chemistry Letters. 48, 128257. DOI:10.1016/j.bmcl.2021.128257. (2021)
  13. Okumura, S., Hirano, Y., and Komatsu, Y.: Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation. SCI REP. 11(1), 11467. doi:10.1038/s41598-021-90972-3 (2021).
  14. Mie, Y., Katagai, S. and Ikegami, M.: Electrochemical Oxidation of Monosaccharides at Nanoporous Gold with Controlled Atomic Surface Orientation and Non-Enzymatic Galactose Sensing, Sensors 20 (19), 5632. doi:10.3390/s20195632 (2020).
  15. Mie, Y., Takayama, H. and Hirano, Y.:, Facile Control of Surface Crystallographic Orientation of Anodized Nanoporous Gold Catalyst and its Application for Highly Efficient Hydrogen Evolution Reaction, J. Catal., 389, 476-482. doi:doi.org/10.1016/j.jcat.2020.06.023 (2020).
  16. Mie, Y., Takahashi, K., Torii, R., Jingkai, S., Tanaka, T., Sueyoshi, K., Tsujino, H. and Yamashita, T.: Redox State Control of Human Cytoglobin by Direct Electrochemical Method to Investigate its Function in Molecular Basis.Chem. Pharm. Bull., 68, 806-809. doi:10.1248/cpb.c20-00175 (2020).
  17. Mie, Y., Yasutake, Y., Takayama, H. and Tamura, T.: Electrochemically boosted cytochrome P450 reaction that efficiently produces 25-hydroxyvitamin D-3. Journal of Catalysis 384, 30-36. doi:10.1016/j.jcat.2020.02.012 (2020).
  18. Mie, Y., Takahashi, K., Itoga, Y., Sueyoshi, K., Tsujino, H. and Yamashita, T.: Nanoporous gold based electrodes for electrochemical studies of human neuroglobin. Electrochemistry Communications 110. doi:10.1016/j.elecom.2019.106621 (2020).
  19. Ikegami, M., Hirano, Y., Mie, Y. and Komatsu, Y.: Adsorptive Stripping Voltammetry for the Determination of Dissolved Oxygen Using a Mesoporous Pt Microelectrode. J. Electrochem. Soc., 166(6), B542-B546. doi:10.1149/2.0021908jes (2019).
  20. Mie, Y., Yasutake, Y., Ikegami, M. and Tamura, T.: Anodized gold surface enables mediator-free and low-overpotential electrochemical oxidation of NADH: A facile method for the development of an NAD(+)-dependent enzyme biosensor. SENSORS AND ACTUATORS B-CHEMICAL, 288, 512. doi:10.1016/j.snb.2019.03.039 (2019).
  21. Mie, Y., Hirano, Y., Kowata, K., Nakamura, A., Yasunaga, M., Nakajima, Y., Komatsu, Y. Function Control of Anti-microRNA Oligonucleotides Using Interstrand Cross-Linked Duplexes. Mol. Ther. Nucleic Acids., 10, 64–74 doi:10.1016/j.omtn.2017.11.003 (2018)
  22. Hirano, Y., Kojima, N. and Komatsu, Y. Synthesis and Application of Interstrand Cross-Linked Duplexes by Covalently Linking a Pair of Abasic Sites. CURR. PROTOC. NUCLEIC ACID CHEM., 75, e63 doi:10.1002/cpnc.63 (2018).
  23. Okumura, S., Hirano, Y., Maki, Y. and Komatsu, Y. Analysis of time-course drug response in rat cardiomyocytes cultured on a pattern of islands. Analyst., 143 4083-4089 doi:10.1039/c8an01033a (2018).